The 26th annual workers’ compensation report produced by the Academy provides the only comprehensive data on workers’ compensation benefits, coverage, and employer costs for the nation, the states, the District of Columbia, and federal programs. With a five-year study period spanning 2017-2021, this is the second annual report to cover the COVID-19 pandemic period, which permits an early understanding of the adaptation of workers’ compensation to the pandemic and general reversions to pre-pandemic trends. The report includes 19 tables, 7 figures, and 5 appendices detailing outcomes related to workers’ compensation benefits, costs, and coverage.